515-294-9220
Molecular Microbiology & Vaccinology Lab.


Models for Gut-Mediated Horizontal Gene Transfer by Bacterial Plasmid Conjugation
June 30, 2022
Logan C. Ott and Melha Mellata. Front. Micro.

High voltage atmospheric cold plasma treatment inactivates Aspergillus flavus spores and deoxynivalenol toxin
November 5, 2020
Ott LC., HJ Appleton. H Shi, K Keener, and M. Mellata
Food Micro

Reserpine improves Enterobacteriaceae resistance in chicken intestine via neuro-immunometabolic signaling and MEK1/2 activation.
December 3, 2021
Graham A. J. Redweik, Michael H. Kogut, Ryan J. Arsenault, Mark Lyte & Melha Mellata. Nature (Com Bio)
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Drosophila Model for Gut-Mediated Horizontal Transfer of Narrow- and Broad-Host-Range Plasmids
October 20, 2021
Logan C Ott; Mark Engelken, Sara M. Scott, Elizabeth M. McNeill, and Melha Mellata
mSphere

Evaluation of Live Bacterial Prophylactics to Decrease IncF Plasmid Transfer and Association With Intestinal Small RNAs
January 14, 2021
Redweik GAJ., MK Horak, R. Hoven, LC. Ott, and M Mellata
Front. Micro

Bacteria Broadly-Resistant to Last Resort Antibiotics Detected in Commercial Chicken Farms
January 9, 2021
Jochum JM., GAP. Redweik. LC. Ott, and M. Mellata
Microorganisms

Transcriptomic Analysis of Shiga Toxin-Producing Escherichia coli during Initial Contact with Cattle Colonic Explants
October 27, 2020
Stromberg ZR, RE Masonbrink, and M. Mellata
Front. Vet. Sci.

Live Bacterial Prophylactics in Modern Poultry
October 28, 2020

Microbiome and Biological Blood Marker Changes in Hens at Different Laying Stages in Conventional and Cage Free Housings
March 19, 2020
Van Goor A., GAJ. Redweik, ZR. Stromberg, , H. Xin and M. Mellata
Poultry Science

Oral Treatments with Probiotics and Live Salmonella Vaccine induce Unique Changes in Gut Neurochemicals and Microbiome in Chickens.
January 15, 2020
Redweik GAJ, K. Daniels, AJ. Severin, M. Lyte, and Melha Mellata.
Front Micro.

Protection against Avian Pathogenic Escherichia coli and Salmonella Kentucky exhibited in Chickens given both Probiotics and Live Salmonella Vaccine.
February, 2020
Redweik GAJ, Z R. Stromberg, A Van Goor, and M Mellata
Poultry Science

Mouse Genetic Background Affects Transfer of an Antibiotic Resistance Plasmid in the Gastrointestinal Tract
January 29, 2020
Logan C Ott #, Zachary R Stromberg #, Graham A J Redweik, Michael J Wannemuehler, and Melha Mellata
mSphere.

Oral Treatments With Probiotics and Live Salmonella Vaccine Induce Unique Changes in Gut Neurochemicals and Microbiome in Chickens
January 15, 2020
Redweik GAJ, k Karrie Daniels, AJ Severin, M. Lyte and M Mellata.
Front Micro

Characterization of Spleen Transcriptome and Immunity Against Avian Colibacillosis After Immunization with Recombinant Attenuated Salmonella Vaccine Strains.
August 21, 2018
Stromberg ZR, A Van Goor, GAJ. Redweik, and M. Mellata
Front. Vet. Sci

Protection against Avian Pathogenic Escherichia coli and Salmonella Kentucky exhibited in Chickens given both Probiotics and Live Salmonella Vaccine
December 11, 2019
Redweik GAJ, Z R. Stromberg, A Van Goor, and M Mellata.
Poult Sci.

Detection and Cell-Based Methods for Evaluating Non-O157 Shiga Toxin-Producing Escherichia coli from Cattle
March 1, 2018
Stromberg ZR, GAJ Redweik, and M. Mellata
Foodborne Pathog Dis

Characterization of Spleen Transcriptome and Immunity Against Avian Colibacillosis After Immunization with Recombinant Attenuated Salmonella Vaccine Strains.
August 21, 2018
Stromberg ZR, A Van Goor, GAJ. Redweik, and M. Mellata
Front. Vet. Sci

Pathogenic and Non-pathogenic Escherichia coli Colonization and Host Inflammatory Response in a Defined Microbiota Mouse Model
November 16, 2018
Stromberg ZR, A. Van Goor GAJ. Redweik, MJ. Wymore Brand, MJ. Wannemuehler, and M. Mellata
Dis. Mod. Mech.

Characterization of Spleen Transcriptome and Immunity Against Avian Colibacillosis After Immunization with Recombinant Attenuated Salmonella Vaccine Strains.
August 21, 2018
Stromberg ZR, A Van Goor, GAJ. Redweik, and M. Mellata
Front. Vet. Sci

Evaluation of Recombinant Attenuated Salmonella Vaccine Strains for Broad Protection against Extraintestinal Pathogenic Escherichia coli
October 9, 2017
Maddux JT., ZR. Stromberg, R. Curtiss 3rd, and M. Mellata
Front. Immunol

A Recombinant Multi-Antigen Vaccine with Broad Protection Potential against Avian Pathogenic Escherichia coli.
August 24, 2017
Van Goor A., ZR. Stromberg, and M. Mellata
PlosOne

Escherichia coli Isolates from Commercial Chicken Meat and Eggs Cause Sepsis, Meningitis, and Urinary Tract Infection in Rodent Models of Human Infection.
July 13, 2017
Mellata M., JR. Johnson, and R. Curtiss III
Zoonoses and public Health

Evaluation of Escherichia coli Isolates from Healthy Poultry to Determine their Potential risk to Poultry and Human Health.
July 3, 2017
Stromberg ZR., JM. Fairbrother, A. Van Goor, JR. Johnson, B. Johnston, R. Curtiss III, M. Mellata
PlosOne

Publication of Latest Findings
January 25, 2025
This is a citation of your published work. Make sure you list the precise publishing medium of your work, whether it be a book, an essay, an article, or a research manuscript. If your work appears only on certain pages, include those details and the date of publication to make it easier for your readers to identify and find your piece.
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High voltage atmospheric cold plasma inactivation of Listeria monocytogenes in fresh Queso Fresco cheese
March 10, 2022
Logan C. Ott, Jared Jochum, Lauren Burrough, Stephanie Clark, Kevin Keener, Melha Mellata. Food Micro.
Get in touch to learn more.

Published Work
References and Links to Papers
Here you will find information about the research publications to come out of the Mellata Lab. We’ve had many wonderful lab members be involved in a variety of different projects since we first started back in 2015, and are proud to showcase their hard work with the list of publications below.

Reserpine improves Enterobacteriaceae resistance in chicken intestine via neuro-immunometabolic signaling and MEK1/2 activation.
December 3, 2021
Graham A. J. Redweik, Michael H. Kogut, Ryan J. Arsenault, Mark Lyte & Melha Mellata. Nature (Com Bio)

Drosophila Model for Gut-Mediated Horizontal Transfer of Narrow- and Broad-Host-Range Plasmids
October 20, 2021
Logan C Ott; Mark Engelken, Sara M. Scott, Elizabeth M. McNeill, and Melha Mellata
mSphere

Evaluation of Live Bacterial Prophylactics to Decrease IncF Plasmid Transfer and Association With Intestinal Small RNAs
January 14, 2021
Redweik GAJ., MK Horak, R. Hoven, LC. Ott, and M Mellata
Front. Micro

Bacteria Broadly-Resistant to Last Resort Antibiotics Detected in Commercial Chicken Farms
January 9, 2021
Jochum JM., GAP. Redweik. LC. Ott, and M. Mellata
Microorganisms

High voltage atmospheric cold plasma treatment inactivates Aspergillus flavus spores and deoxynivalenol toxin
November 5, 2020
Ott LC., HJ Appleton. H Shi, K Keener, and M. Mellata
Food Micro

Transcriptomic Analysis of Shiga Toxin-Producing Escherichia coli during Initial Contact with Cattle Colonic Explants
October 27, 2020
Stromberg ZR, RE Masonbrink, and M. Mellata
Front. Vet. Sci.

Live Bacterial Prophylactics in Modern Poultry
October 28, 2020

Microbiome and Biological Blood Marker Changes in Hens at Different Laying Stages in Conventional and Cage Free Housings
March 19, 2020
Van Goor A., GAJ. Redweik, ZR. Stromberg, , H. Xin and M. Mellata
Poultry Science

Oral Treatments with Probiotics and Live Salmonella Vaccine induce Unique Changes in Gut Neurochemicals and Microbiome in Chickens.
January 15, 2020
Redweik GAJ, K. Daniels, AJ. Severin, M. Lyte, and Melha Mellata.
Front Micro.

Protection against Avian Pathogenic Escherichia coli and Salmonella Kentucky exhibited in Chickens given both Probiotics and Live Salmonella Vaccine.
February, 2020
Redweik GAJ, Z R. Stromberg, A Van Goor, and M Mellata
Poultry Science

Mouse Genetic Background Affects Transfer of an Antibiotic Resistance Plasmid in the Gastrointestinal Tract
January 29, 2020
Logan C Ott #, Zachary R Stromberg #, Graham A J Redweik, Michael J Wannemuehler, and Melha Mellata
mSphere.

Oral Treatments With Probiotics and Live Salmonella Vaccine Induce Unique Changes in Gut Neurochemicals and Microbiome in Chickens
January 15, 2020
Redweik GAJ, k Karrie Daniels, AJ Severin, M. Lyte and M Mellata.
Front Micro

Characterization of Spleen Transcriptome and Immunity Against Avian Colibacillosis After Immunization with Recombinant Attenuated Salmonella Vaccine Strains.
August 21, 2018
Stromberg ZR, A Van Goor, GAJ. Redweik, and M. Mellata
Front. Vet. Sci

Protection against Avian Pathogenic Escherichia coli and Salmonella Kentucky exhibited in Chickens given both Probiotics and Live Salmonella Vaccine
December 11, 2019
Redweik GAJ, Z R. Stromberg, A Van Goor, and M Mellata.
Poult Sci.

Detection and Cell-Based Methods for Evaluating Non-O157 Shiga Toxin-Producing Escherichia coli from Cattle
March 1, 2018
Stromberg ZR, GAJ Redweik, and M. Mellata
Foodborne Pathog Dis

Characterization of Spleen Transcriptome and Immunity Against Avian Colibacillosis After Immunization with Recombinant Attenuated Salmonella Vaccine Strains.
August 21, 2018
Stromberg ZR, A Van Goor, GAJ. Redweik, and M. Mellata
Front. Vet. Sci

Pathogenic and Non-pathogenic Escherichia coli Colonization and Host Inflammatory Response in a Defined Microbiota Mouse Model
November 16, 2018
Stromberg ZR, A. Van Goor GAJ. Redweik, MJ. Wymore Brand, MJ. Wannemuehler, and M. Mellata
Dis. Mod. Mech.

Characterization of Spleen Transcriptome and Immunity Against Avian Colibacillosis After Immunization with Recombinant Attenuated Salmonella Vaccine Strains.
August 21, 2018
Stromberg ZR, A Van Goor, GAJ. Redweik, and M. Mellata
Front. Vet. Sci

Evaluation of Recombinant Attenuated Salmonella Vaccine Strains for Broad Protection against Extraintestinal Pathogenic Escherichia coli
October 9, 2017
Maddux JT., ZR. Stromberg, R. Curtiss 3rd, and M. Mellata
Front. Immunol

A Recombinant Multi-Antigen Vaccine with Broad Protection Potential against Avian Pathogenic Escherichia coli.
August 24, 2017
Van Goor A., ZR. Stromberg, and M. Mellata
PlosOne

Escherichia coli Isolates from Commercial Chicken Meat and Eggs Cause Sepsis, Meningitis, and Urinary Tract Infection in Rodent Models of Human Infection.
July 13, 2017
Mellata M., JR. Johnson, and R. Curtiss III
Zoonoses and public Health

Evaluation of Escherichia coli Isolates from Healthy Poultry to Determine their Potential risk to Poultry and Human Health.
July 3, 2017
Stromberg ZR., JM. Fairbrother, A. Van Goor, JR. Johnson, B. Johnston, R. Curtiss III, M. Mellata
PlosOne
Get in touch to learn more.

Published Work
References and Links to Papers
Here you will find information about the research publications to come out of the Mellata Lab. We’ve had many wonderful lab members be involved in a variety of different projects since we first started back in 2015, and are proud to showcase their hard work with the list of publications below.

Transcriptomic Analysis of Shiga Toxin-Producing Escherichia coli during Initial Contact with Cattle Colonic Explants
October 27, 2020
Stromberg ZR, RE Masonbrink, and M. Mellata
Front. Vet. Sci.

Oral Treatments with Probiotics and Live Salmonella Vaccine induce Unique Changes in Gut Neurochemicals and Microbiome in Chickens.
January 15, 2020
Redweik GAJ, K. Daniels, AJ. Severin, M. Lyte, and Melha Mellata.
Front Micro.

Microbiome and Biological Blood Marker Changes in Hens at Different Laying Stages in Conventional and Cage Free Housings
March 19, 2020
Van Goor A., GAJ. Redweik, ZR. Stromberg, , H. Xin and M. Mellata
Poultry Science

Protection against Avian Pathogenic Escherichia coli and Salmonella Kentucky exhibited in Chickens given both Probiotics and Live Salmonella Vaccine.
February, 2020
Redweik GAJ, Z R. Stromberg, A Van Goor, and M Mellata
Poultry Science

Mouse Genetic Background Affects Transfer of an Antibiotic Resistance Plasmid in the Gastrointestinal Tract
January 29, 2020
Logan C Ott #, Zachary R Stromberg #, Graham A J Redweik, Michael J Wannemuehler, and Melha Mellata
mSphere.

Oral Treatments With Probiotics and Live Salmonella Vaccine Induce Unique Changes in Gut Neurochemicals and Microbiome in Chickens
January 15, 2020
Redweik GAJ, k Karrie Daniels, AJ Severin, M. Lyte and M Mellata.
Front Micro

Characterization of Spleen Transcriptome and Immunity Against Avian Colibacillosis After Immunization with Recombinant Attenuated Salmonella Vaccine Strains.
August 21, 2018
Stromberg ZR, A Van Goor, GAJ. Redweik, and M. Mellata
Front. Vet. Sci

Protection against Avian Pathogenic Escherichia coli and Salmonella Kentucky exhibited in Chickens given both Probiotics and Live Salmonella Vaccine
December 11, 2019
Redweik GAJ, Z R. Stromberg, A Van Goor, and M Mellata.
Poult Sci.

Detection and Cell-Based Methods for Evaluating Non-O157 Shiga Toxin-Producing Escherichia coli from Cattle
March 1, 2018
Stromberg ZR, GAJ Redweik, and M. Mellata
Foodborne Pathog Dis

Characterization of Spleen Transcriptome and Immunity Against Avian Colibacillosis After Immunization with Recombinant Attenuated Salmonella Vaccine Strains.
August 21, 2018
Stromberg ZR, A Van Goor, GAJ. Redweik, and M. Mellata
Front. Vet. Sci

Pathogenic and Non-pathogenic Escherichia coli Colonization and Host Inflammatory Response in a Defined Microbiota Mouse Model
November 16, 2018
Stromberg ZR, A. Van Goor GAJ. Redweik, MJ. Wymore Brand, MJ. Wannemuehler, and M. Mellata
Dis. Mod. Mech.

Characterization of Spleen Transcriptome and Immunity Against Avian Colibacillosis After Immunization with Recombinant Attenuated Salmonella Vaccine Strains.
August 21, 2018
Stromberg ZR, A Van Goor, GAJ. Redweik, and M. Mellata
Front. Vet. Sci

Evaluation of Recombinant Attenuated Salmonella Vaccine Strains for Broad Protection against Extraintestinal Pathogenic Escherichia coli
October 9, 2017
Maddux JT., ZR. Stromberg, R. Curtiss 3rd, and M. Mellata
Front. Immunol

A Recombinant Multi-Antigen Vaccine with Broad Protection Potential against Avian Pathogenic Escherichia coli.
August 24, 2017
Van Goor A., ZR. Stromberg, and M. Mellata
PlosOne

Escherichia coli Isolates from Commercial Chicken Meat and Eggs Cause Sepsis, Meningitis, and Urinary Tract Infection in Rodent Models of Human Infection.
July 13, 2017
Mellata M., JR. Johnson, and R. Curtiss III
Zoonoses and public Health

Evaluation of Escherichia coli Isolates from Healthy Poultry to Determine their Potential risk to Poultry and Human Health.
July 3, 2017
Stromberg ZR., JM. Fairbrother, A. Van Goor, JR. Johnson, B. Johnston, R. Curtiss III, M. Mellata
PlosOne
Get in touch to learn more.